Abstract:

Electrochemical nanometer immunosensor has the characteristics of simple operation, accuracy, high sensitivity
and good selectivity, where biological sensing chips are used to detect the interaction between antigen and antibody. It has
a wide range of applications in the fields of medicine, food, environmental monitoring, drug screening and life science. In
this paper, we compare electrochemical nanometer immunosensor with instrumental analysis, immunological detection,
polymerase chain reaction (PCR)-based molecular biology detection techniques and surface plasmon resonance (SPR)- and
biolayer interferometry (BLI)-based detection techniques for their advantages and drawbacks. We also discusse the two
key issues electrochemical nanometer immunosensor itself is facing: immune binding signal amplification processing and
commercial application. Finally, we overview the current applications of nanomaterial in the immunosensor and those of
electrochemical nanometer immunosensor in food detection, and discuss its future prospects in this area.

Key words: electrochemical, nonmaterial, immunosensor, food detection, antibody