Optimization of Formulation and Processing of Puerariae Radix Extract-Spirulina Compound Tablets

doi:10.7506/spkx1002-6630-201414013

Abstract

Abstract:

Puerariae Radix-Spirulina compound tablets were made from Puerariae Radix extract (rich in flavonoids) and
Spirulina powder by direct pressing method. The formulation was optimized by single-factor and orthogonal array designs
through analysis of variance (ANOVA) and range analysis. The results obtained in this research showed that the optimum
excipient consisted of 1.5% silicon dioxide, 1% microcrystalline cellulose and 0.25% magnesium stearate, and the optimum
tablet formulation was composed of 10% Puerariae Radix extract, 87.5% Spirulina powder with a moisture content of about
7.5% and 2.5% excipient. The tableting pressure was 30 kN.

Key words: Puerariae Radix-Spirulina compound tablets, formulation, process

CLC Number:

TS254.4

YANG Sheng-hui, LUO Guang-hong*, ZU Ting-xun, WANG Dan-xia, CHEN Tian-ren. Optimization of Formulation and Processing of Puerariae Radix Extract-Spirulina Compound Tablets[J]. FOOD SCIENCE, doi: 10.7506/spkx1002-6630-201414013.

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Optimization of Formulation and Processing of Puerariae Radix Extract-Spirulina Compound Tablets

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