Abstract:

The response surface methodology was used to optimize the superfine grinding of honeysuckle (Flos Lonicerae).
The yields of total flavonoids and total phenols extracted from ground honeysuckle were investigated as a function of
superfine grinding pressure, frequency and time. As a result, a mathematical model was established. The results showed that
all three operating parameters had significant effects on functional components of honeysuckle (P < 0.05). The optimum
process conditions were determined as 0.6 MPa, 14.4 min and 31.3 Hz for superfine grinding pressure, time and frequency,
respectively. Under these conditions, the yields of total flavonoids and total phenols were 1.15% and 0.74%, respectively.

Key words: superfine grinding, honeysuckle, total flavonids, total phenols