Abstract:

In this study, a modified quick, easy, cheap, effective, rugged and safe (QuEChERS ) approach was applied for
the determination of 24 organochlorine pesticide and pyrethroid residues in milk samples by gas chromatography-electron
capture detector (GC-ECD). Milk samples were extracted with acetonitrile, purified with the modified QuEChERS approach,
and detected by GC-ECD. The external standard method was used for quantification. Excellent linearities were achieved for
all target analytes in the range of 5–250 μg/L with correlation coefficients greater than 0.99. The limits of detection (LODs)
ranged from 0.06 to 0.30 μg/kg. The recoveries were in the range of 85.5%–111.2%, with relative standard deviations (RSDs)
less than 11%. In summary, the proposed method was simple, accurate, efficient and adequate for the rapid screening and
quantitative analysis of organochlorine pesticide and pyrethroid residues in milk.

Key words: QuEChERS (quick, easy, cheap, effective, rugged and safe), gas chromatography, organochlorine, pyrethroid pesticide, milk