Abstract: In this paper, a solid phase extraction-gas chromatography (SPE-GC) method and a comprehensive two dimensional gas chromatography (GC × GC) method were established and compared for the determination of MOSH migration from food contact paper-based products. The results showed that both methods could achieve effective separation and detection of MOSH in the migration solution with a relative standard deviation of 4.3%. Compared with SPE-GC, GC × GC required simpler sample pretreatment and had lower limit of detection (LOD) (1.0 mg/L) and higher recoveries (94.4%–102.4%). The deviation between the quantitative results from the two method was 8.6% for 17 batches of actual samples. It was further found that GC × GC had wider applicability and could be used to detect and quantify the samples which could not be detected by SPE-GC. This study provides important methodological data support for the formulation of new standards.

Key words: paper products, mineral oil, migration, solid phase extraction-gas chromatography, comprehensive two dimensional gas chromatography