Progress in Understanding the Structure-Activity Relationship and Mechanism of Action of Marine Bioactive Peptides

doi:10.7506/spkx1002-6630-20200702-035

FOOD SCIENCE ›› 2021, Vol. 42 ›› Issue (19): 271-280.doi: 10.7506/spkx1002-6630-20200702-035

• Reviews • Previous Articles

Progress in Understanding the Structure-Activity Relationship and Mechanism of Action of Marine Bioactive Peptides

HUANG Muchen, YANG Fujia, CHEN Xu, CAI Xixi, CHEN Xuan, WU Jinhong, ZHANG Heng, ZHANG Jun, WANG Shaoyun

(1. College of Biological Science and Engineering, Fuzhou University, Fuzhou 350108, China; 2. College of Chemical Engineering, Fuzhou University, Fuzhou 350108, China; 3. School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China; 4. Bankpeptide Biological Technology Co., Ltd., Xuancheng 242199, China; 5. Zhongshi Duqing (Shandong) Biotech Co., Ltd., Heze 274108, China)

Published:2021-11-12

Abstract

Abstract: The sea is rich in unique biological resources. Marine-derived proteins are good precursors for developing bioactive peptides. Marine bioactive peptides have broad development and application prospects with the advantages of wide availability, high efficiency and safety. This paper reviews the functional characteristics of marine bioactive peptides including antioxidant peptides, antimicrobial peptides, antifreeze peptides, metal ion chelating peptides and immunomodulatory peptides. Meanwhile, the structure-activity relationship and mechanism of action of these bioactive peptides are elucidated. Future research and development trends for marine bioactive peptides are discussed together with future application prospects. This paper is expected to provide a reference for further research of marine bioactive peptides.

Key words: marine bioactive peptides; structure-activity relationship; mechanism of action

CLC Number:

O629.72

HUANG Muchen, YANG Fujia, CHEN Xu, CAI Xixi, CHEN Xuan, WU Jinhong, ZHANG Heng, ZHANG Jun, WANG Shaoyun. Progress in Understanding the Structure-Activity Relationship and Mechanism of Action of Marine Bioactive Peptides[J]. FOOD SCIENCE, 2021, 42(19): 271-280.

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Progress in Understanding the Structure-Activity Relationship and Mechanism of Action of Marine Bioactive Peptides

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