Abstract: Based on transition metal nickel-based basic carbonate (Ni-CHs) grown in situ on carbon paper (Ni-CHs/CP), prepared by one-step hydrothermal method, a highly sensitive and selective enzyme-free sensor to detect glucose was developed. X-ray diffraction (XRD) and scanning electron microscopy (SEM) were used to identify the phase and characterize the morphology of the material. Cyclic voltammetry (CV) and time-current curve were used to evaluate the performance of the sensor. The results showed that Ni-CHs/CP had the best detection ability for glucose at a low potential of 0.5 V, and the oxidation peak current of the sensor showed an excellent linear relationship with glucose concentration in the range of 0.95 μmol/L–2.623 mmol/L, with a correlation coefficient of 0.998. The detection limit was 0.31 μmol/L (RSN = 3) and response time was 3.5 s. This sensor has good stability and has been successfully used in the detection of actual samples with spiked recoveries of 95.65%–105.56%.

Key words: nickel-base carbonate; non?enzymatic electrochemical sensor for glucose detection; hydrothermal method; beverage