Abstract: Tyrosine derivatives are widely used in the fields of food, medicine and chemical engineering due to their important edible and medicinal values. Based on this, the development of green and efficient methods for obtaining high-value tyrosine derivatives has become a research hotspot. With the development of synthetic biology and metabolic engineering, using microbial cell factories to synthesize high-value tyrosine derivatives is expected to become a green and large-scale production method. Besides, regulating the metabolic pathways of the target products is crucial to improving the production efficiency. Therefore, this article introduces the synthetic pathways and metabolic regulation strategies of tyrosine derivatives, hoping to provide a reference for constructing high-yield engineered strains.

Key words: cell factory; tyrosine derivatives; synthesis pathway; regulatory strategies of metabolic pathways