Abstract: This study systematically analyzed the application status and quality control requirements of fat powder in foods for special medical purposes (FSMP). By statistically analyzing the data of FSMP approved by the State Administration for Market Regulation (SAMR), the study systematically sorted out the usage and species distribution of fat powder in different categories of FSMP, as well as the frequency and compliance of use of wall materials and food additives in FSMP. Furthermore, the study compared multiple national standards, industrial standards and group standards related to fat powder. By referring to the management requirements for FSMP in representative countries combined with the enterprise internal control standards accumulated in routine review work and industry research information, this study comprehensively discussed the quality control system of fat powder from multiple dimensions, including physicochemical indicators, contaminant, mycotoxin and microbial limits, pesticide residues, and other key indicators. Finally, specific recommendations on the application and quality control of fat powder in FSMP were put forward, including 1) incorporating the requirements for the type and content of fatty acids into the quality requirements of fat powder, 2) reasonably selecting wall materials and food additives for fat powder based on the nutritional needs of the target population and relevant regulatory requirements, 3) implementing hierarchical quality control of fat powder at the raw material and finished product stages, and 4) improving the limit requirements for 3-chloro-1,2-propanediol (3-MCPD) and its esters as well as glycidyl esters based on risk assessment. This study provides a scientific basis for the formulation of standards for the application and quality control of fat powder in FSMP, ensuring the quality safety and nutritional effectiveness of FSMP.

Key words: foods for special medical purposes; fat powder; medium-chain triglyceride powder; quality standards