Abstract:  Metbyln-alkyl ethyl, propyl, butyi, amyl, nonyl, fumarates were preparaed, the yields were over 85% These diesters could effectively prolong adaptive phuse(t0) of bacteria from deteriorate ham sauage for 2-8 times, sharten the half logdrithmic growth phase(t0.5) to 1/3-2/3, t0.5/t0 values were only 1/28-1/6 of the control. Methyln-alkyl fumarates significanily inhibited the growth and induced the autolysis of bacteria.

Key words: Preventives Methyln-alkyl famarates Preparation Antibacterial activity