Abstract: The purpose of this paper was to investigate the effects of Cordyceps sinensis mycelium on expectoration and cough-orelief.Two-month mice were selected and divided into three groups: control group, low-dose group(0.5g/kg.bw) and high-dose group(1.0g/kg.bw). We conducted the experiment after feeding 17 days and 27 days. The results show that, comparing with the control group, the low-dose Cordyceps decrease the cough times 44.4%(P<0.05)and inhibit inflammation swelling at the ear area of mice 40.2%(P<0.05). The high-dose Cordyceps sinensis mycelium could prolong the incubation period of cough 88.4%(P<0.01),decrease the times of cough 49.4%(P<0.05),inhibit inflammation swelling at the ear area of mice 36.4%(P<0.05) and also accelerate phlegm displacement of mice 75.0%(P<0.01). The ex-vivo experiment showed that Cordyceps sinensis mycelium could inhibit the increment of pneumonocccus, beta streptococcus and staphylococcus aureus. Cordyceps sinensis mycelium had obviously functions of expectorant effect, cough-relief, antiseptisis and antfi-inflammatory effect.

Key words: Cordyceps sinensis mycelium, Cough-relief, Expectorant effect, Antisepticize and Inflammation