Abstract: With the result of rapidly increasing number of completed and ongoing genome sequences of food-related microbes,comparative and functional genomics approaches are being developed for employing these data in the benefit of the food biotechnology.These developments not only offer a better understanding of microbial cell physiology and its metabolic function but also provide mant possibilities to improve the functional properties of foods by Utilizying food grade microorganisms and to increasc the safety of foods as well.

Key words: Comparative genomics , Functional genomics , Food microorganisms