Abstract: Removing of toxic component -ginkgolic acids test from Ginkgo biloba leaves by Supercritical CO2 Fluid Extractionwas studied. The effect of operating pressure, operating temperature and total volume of CO2 on rate of removing ginkgolic acidswere investigated by using orthogonal experiments. The results showed that ginkgolic acids in Ginkgo biloba leaves could be removedeffectively by Supercritical CO2 Fluid Extraction. The optimum extraction conditions were obtained at 30MPa and 60℃ with totalCO2 volume of 600L. The rate of removing ginkgolic acids could be up to 79.1%. The content of ginkgolic acids in extracted leavesof Ginkgo biloba by Supercritical CO2 was 0.25%. The new method was developed for a high quality Ginkgo biloba teasproduction.

Key words: leaves of Gingko biloba, teas of Gingko biloba, ginkgolic acids, supercritical CO2 fluid extraction