The Experimental Study of CPS Anti-tumor

Abstract

Abstract: Objective: Discuss about the anti-tumor effect and mechanism of Chicory Polysaccharide(CPS), which provides thebasis of clinical application. Method: Divide mice (injected by tumor cell) into 5 groups randomly, each group has 10 mice, inwhich both male and female take one half. Administer Chicory Polysaccharide(CPS) 10 days continuously. 24h after administration,kill and weigh them. Separate and weigh tumors in right axillary fossa in mice. Result: Chicory Polysaccharide(CPS) inhibitgrowth of sarcoma S180, liver carcinoma HEP and gastric carcinoma MFC cell bearing tumor mice obviously, it can suppress thegrowth of S180 significantly and prolong the survival time even at a lower dose. Meanwhile, it can increase the phagocyte indexA, expuragation index K, thymus coefficient and increase the transform function of the lymphocyte in vitro. Conclusion: ChicoryPolysaccharide(CPS) has obvious effect on anti-tumor.

Key words: Chicory Polysaccharide(CPS), anti-tumor

CHEN Li-Ge, CHANG You-Quan, ZHENG Hong-Yan, MA Jin-Rong, CHANG Xi-Tao. The Experimental Study of CPS Anti-tumor[J]. FOOD SCIENCE, 2004, 25(11): 276-280.

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The Experimental Study of CPS Anti-tumor

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