Isolation and Function of Plant Insulin Isolated from Momordica charantia

Abstract

Abstract: Isolation method of plant insulin from Momordica charantia was improved and its hypoglycemic function was probed. Plant insulin was extracted with organic acid and ethanol and purified with Sephadex G-50 gel filtration and reversed-phase high performance liquid chromatography (RP-HPLC) from Momordica charantia. The method was better than thin-layer chromatogra- phy technology. The peptide injected subcutaneously could lower blood sugar of normal mice and alloxan-induced diabetic mice.

Key words: Momordica charantia, plant insulin, isolation, diabetes

SHENG Qing-Kai, YAO Hui-Yuan. Isolation and Function of Plant Insulin Isolated from Momordica charantia[J]. FOOD SCIENCE, 2005, 26(1): 223-225.

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Isolation and Function of Plant Insulin Isolated from Momordica charantia

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