Abstract: Objective:To study on the anti-hypoxia function and nutrition chemistry in Danshen extract. Method: To use mice to test on anti-hypoxia activity of danshen extract and the active components to be determined by HPLC combined with chemical standard materials. Nutritional elements were also assayed with different procedure according to their characteristics. The bioactive results were compared to functional and nutritional components. Results: It showed that the Danshen extract could prolong the serving time of testing rats. The functional and nutritional components of anti-hypoxia function were rich in the extract. 5 kinds of active components were separated as tanshinoneIIA1.43%, crytotanshinone 0.51%, tanshinoneI 0.1%, 3,4- Dihydroxyphenyllactic acid 2.14%, protocatechuic aldehyde 0.33%, polysaccharide 4.6% in alcohol extract. The contents of vitamin C, E and carotene were 0.722 mg, 25.9 mg and 0.47 mg, respectively. Conclusions: Danshen extract had the function role of anti-hypoxia based on the functional and nutritional factors. It could be used as health improving additives.

Key words: Danshen, extract, anti-oxygen, nutrition chemistry