Abstract: Objective: Discuss about the anti-tumor effect and mechanism of MVET, which provides the basis of clinical application. Method: Divide mice (injected by tumor cell) into 5 groups randomly, each group has 10 mice, in which both male and female take one half. Administer MVET 10 days continuously. 24h after administration, kill and weigh them. Separate and weigh tumors in right axillary fossa in mice. Result: MVET inhibit growth of sarcoma S180, liver carcinoma HEP and gastric carcinoma MFC cell bearing tumor mice obviously, it can suppress the growth of S180 significantly and prolong the survival time even at a lower dose. Meanwhile, it can increase the phagocyte index A, expuragation index K, thymus coefficient and increase the transform function of the lymphocyte in vitro. Conclusion: MVET has obvious anti-tumor effect.

Key words: melon vines effective part(MVET), anti-tumor