FOOD SCIENCE ›› 2006, Vol. 27 ›› Issue (1): 210-212.

Previous Articles     Next Articles

Effect of Goat Plancenta Immunoregulatory Factor on Immunological Function of Mice Irradiated by ~(60)Co-γray

 FANG  Liao-Qiong, HE  Cheng-Ming, NIU  Rong, ZHONG  Ying-Ying, WEI  Hong   

  1. 1.Department of Laboratory Animals, The Third Military Medicl University;2.College of Bionengineering, Chongqing Institute of Technology, Chongqing 400050,China 3.College of Sericultural Science and Biotechnology, Southwest University.
  • Online:2006-01-15 Published:2011-09-05

RichHTML

0

PDF (PC)

364

Abstract: The aim of this study was to investigate the effects of goat plancenta immunoregulatory factor(GPIF) on the immunological function of mice irradiated by 60Co-γray. This study was carried out by determining the rat of splenic lymphocytes induced by ConA or LPS with MTT test, the ability of DTH with the changes of weight of ear’s piece, and the levels of IgG in serum with ELISA test. The results indicated that GPIF could efficiently increase the numbers of splenic lymphocytes irradiated by 60Co-γray, enhance the ability of delayed type hypersensitivity, and increase the level of IgG in serum of mice wholly irradiated by 60Co-γray. It was concluded that GPIF could recover the specific immunity function of mice with the immunity damage by irradiation and increase the ability of mice with irradiation resistance.

Key words: GPIF (goat plancenta immunoregulatory factor), irradiation-damage, specific immunity