Abstract:  To study the antifatigue effect of flavonoids from sweet potato vines(FSPV), three doses (100, 200 and 400mg/kg bw·d) of FSPV respectively with 0.9% sodium chloride solution as control were fed to mice by instil-gavage. After 10 days, the swimming time was determined by stopwatch, and the fatigue indexes, such as blood urea nitrogen(BUN), serum lactic dehydrogenase(LDH) and liver and muscle glycogen, were assayed respectively by reagent boxes. The results showed that FSPV could prolong the swimming time and meanwhile had remarkable effects on increasing the serum LDH activity and the reserves of liver and muscle glycogen, and also decreasing increment of BUN after exercise. Finally, it was found that FSPV had obvious antifatigue effect and the medium dose of FSPV (200mg/kg bw·d) was optimum.

Key words: sweet potato vines, flavonoids from sweet potato vines(FSPV), antifatigue