Study on Separation and Purification Technology of Sophora alopecuroides L.

FOOD SCIENCE ›› 2007, Vol. 28 ›› Issue (1): 32-36.

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Study on Separation and Purification Technology of Sophora alopecuroides L.

HU Yan-Li, GUO Li, JIA Xiao-Hong

1.Key Laboratory of Xinjiang Phytomedicine Resources, Ministry of Education, Shihezi 832002, China; 2.School of Tea and Food Science and Technology, Anhui Agricultural University, Hefei 230036, China; 3.School of Food Science, Xinjiang Agricultural University, Urumqi 830052, China

Online:2007-01-15 Published:2011-12-31

Abstract

Abstract: The aim of this paper was to research an optimumly separated and purified method of Sophora alopecuroides L. The results of experiment determined that the most effective separating and purifing method for each ingredient in Sophora alopecuroides L. was a combined one by using alumina column followed recrystallization. Besides, the matrine and oxymatrine crystals obtained respectively from this experiment were analysed for their purification by high performance liquid chromatog- raphy (HPLC). Finally, we found that the purities of the two pured alkaloids both exceed 98%.

Key words: Sophora alopecuroides L., oxymatrine, matrine, separation and purification

HU Yan-Li, GUO Li, JIA Xiao-Hong. Study on Separation and Purification Technology of Sophora alopecuroides L.[J]. FOOD SCIENCE, 2007, 28(1): 32-36.

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