Abstract: Isoamyl acetate was synthetized from acetic acid and isoamyl alcohol with NaHSO4·H2O+AlCl3·6H2O as the catalyst. The effects of reaction conditions on the esterification rate were investigated. The optimum reaction conditions were obtained as follows: acetic acid to isoamyl alcohol molar ratio=1:1.2, NaHSO4·H2O+AlCl3·6H2O as the catalyst, n(AlCl3· 6H2O):n(NaHSO4·H2O)=1:1.5, w(catalyst)=2.0%, w(water carrying reagent toluene)=20%, reaction temperature 115±5℃, and reaction time 90min. Esterification rate is 98.4%. The experimental results showed that NaHSO4·H2O+AlCl3·6H2O is an excellent catalyst for the synthesis of isoamyl acetate, with higher yields and practical application value.

Key words: perfume； isoamyl acetate； AlCl3·, 6H2O+NaHSO4·, H2O catalyst； green synthesis；