FOOD SCIENCE ›› 2007, Vol. 28 ›› Issue (2): 289-292.

Previous Articles     Next Articles

Preparation and Effects on Angiotensin I-Converting Enzyme Activity of Rapeseed Peptide(RSP) in Rats

 XUE  Zhao-Hui, WEI  Wan-Cong, WU  Mou-Cheng, ZHOU  Zhi-Jiang, LIU  Chun-Quan   

  1. 1.College of Agriculture and Bioengineering, Tianjin University, Tianjin 300072, China; 2.Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China; 3.College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China; 4.Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China
  • Online:2007-02-15 Published:2011-12-31

RichHTML

3

PDF (PC)

239

Abstract: Objective :To isolate the Rapeseed Albumin hydrolysate and study the effects on the activity of angiotension Ⅰ- converting enzyme(ACE) of the rapeseed peptides on rats and the grades. Methods: ①Using Sephadex G-25 column with water as eluant; ②Spontaneously hypertensive rats(SHR) were used as animal model, the changes of ACE activity were investigated in vitro. Results :Three purified grades were isolated(RSP-Ⅰ,Ⅱ, and Ⅲ) by Sephadex G-25 column. RSP-R and three fractions exert remarkable inhibition on ACE activity, among which RSP-3 showed the highest inhibition. Conclusion: Proteolysis of rapeseed albumin can result ACE inhibitory activity in peptides. The high quality of RSP can be used directly in the supplementation of foods and can also widen the field of application of rapeseed albumin.

Key words: rapeseed albumin, rapeseed peptide(RSP), angiotensin I-converting enzyme(ACE) inhibitors, lotensin, bio-active peptides