FOOD SCIENCE ›› 2007, Vol. 28 ›› Issue (3): 77-79.

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Study on Biosynthetic Pathway of Antibiotic Monascus Pigments

 ZHU  Lei, CHANG  Hui-Ping, WEI  Bing, TANG  Xin-Yun, LI  Kun-Yang   

  1. College of Life Science, Anhui Agricultural University, Hefei 230036, China
  • Online:2007-03-15 Published:2011-12-31

Abstract: Feed stimulating experiments were used to confirm precursors of monascus pigments. Different amino acids and branched fatty acids effects on monascus pigments production were investigated. The results showed that the amino acids and branched fatty acids, such as valine, isoleucine, methionine, glutamine, acetate, propionate can act as precursors and stimulate pigments biosynthesis. Besides, these compounds have the same character that all can be transformed to precursors of polyketide biosynthesis. So the polyketide pathway is presumed to be the main biosynthetic pathway of antibiotic monascus pigments.

Key words: monascus pigments, polyketide, biosynthesis