FOOD SCIENCE ›› 2007, Vol. 28 ›› Issue (7): 486-489.

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Antioxidation Effects of Wheat Germ Protein Hydrolysates on Mice

 CHENG  Yun-Hui, WEN  Xin-Hua, WANG  Zhang   

  1. 1.College of Biology and Food Engineering, Changsha University of Science and Technology, Changsha 410076, China; 2.Hunan Business College, Changsha 410205, China; 3.School of Food Science and Technology, Southern Yangtze University, Wuxi 214036, China
  • Online:2007-07-15 Published:2011-10-24

Abstract: To study the effects of wheat germ protein hydrolysates(WGPHs) in different doses on the serum antioxidant activities in mice.Eighty Kunming mice were divided into two big groups of normal fat feed and high fat feed, one big group were divided into 4 groups: control group, low dose of WGPHs group, medium dose of WGPHs group and high dose of WGPHs group. The mice supplemented with physiological saline and WGPHs at 100, 500, 1000 mg/kg·d respectively by gavage one time a day. The mice were euthanatized after 30 days. The activities of SOD,GSH-Px and the level of MDA were determined. The results showed that the content of MDA in the serum reduced (p< 0.01), the activities of SOD and GSH-Px increased (p <0.01) significantly in the serum; The activities of SOD, GSH-Px increased while the contents of MDA decreased in the experimental group dose-dependently. WGPHs can promoted the abilities of antioxidation of mice.

Key words: wheat germ protein hydrolysates, superoxide dismutases, glutathione peroxidase, malondialdehyde, antioxidation