Study on Biological Efficacy of Dihydromyricetin

FOOD SCIENCE ›› 2008, Vol. 29 ›› Issue (11): 622-625.

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Study on Biological Efficacy of Dihydromyricetin

XU Jing-Juan, YAO Mao-Jun, WU Min-Chen

1.School of Medicine and Pharmaceutics,Jiangnan University,Wuxi 214122,China;2.Institute of Food Science,Jishou University,Jishou 416000,China

Online:2008-11-15 Published:2011-12-08

Abstract

Abstract: This study aimed to investigate the pharmacological effect of the flavonoid,dihydromyricetin(DMY) extracted from Ampelopsis grossedentata.The results showed that its toxicity is very slight,and the greatest tolerance of oral gavage rats is 5.0 g/kg.DMY adminitered to mice by gavage for 30 days can effectively prevent the alcohol-induced liver GSH depletion and MDA content increase,reduce the TG content,ease fatty degeneration of liver cells caused by alcohol.So DMY is known as a strong antioxidant,and can effectively prevent alcohol-induced liver injury.Therefore,DMY as natural antioxidant has a good development prospect.

Key words: dihydromyricetin, biological efficacy

XU Jing-Juan, YAO Mao-Jun, WU Min-Chen. Study on Biological Efficacy of Dihydromyricetin[J]. FOOD SCIENCE, 2008, 29(11): 622-625.

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Study on Biological Efficacy of Dihydromyricetin

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