Ordered Assemblies of Water-Soluble Chitosan as Carriers for Vitamin C

Abstract

Abstract: Two ordered assemblies of water-soluble chitosan were formed in aqueous solution at various chitosan concentrations and temperatures. Steady and dynamic rheological properties of both assemblies were investigated at different temperatures. Meanwhile, the effect of both assemblies as separate carriers for vitamin C on sustained release and stability of vitamin C was determined. The steady rheological curves indicated that both assemblies had strong pseudoplastic property. The dynamic rheological curves revealed that the assembly I could be fitted with Maxwell model under the condition of low frequency and performed as an elastomer under the condition of high frequency. In the tested frequency range, the loss modulus(G＇＇) of the assembly Ⅱ was always lower than its storage modulus(G＇). Therefore, both assemblies allows sustained release and stability maintenance of vitamin C.

Key words: water-soluble chitosan, ordered assembly, rheological property, vitamin C, sustained release

CLC Number:

O647.2

Zhen LI zhong-Ni WANG Wu ZHOU Feng LIU. Ordered Assemblies of Water-Soluble Chitosan as Carriers for Vitamin C[J]. FOOD SCIENCE, 2012, 33(17): 30-34.

References

[1]SHAHIDI F, ARACHCHI J K V, JEON Y J.Food applications of chitin and chitosans[J].,1999,10(2):37-51
[2]SAKURAI K, SHIBANO T, KIMURA K et al.Cyrstal sturcutre of chitosanII.molecular packing in nitcellofcyrstal[J].,1988,93(3):147-151
[3]ROUT D K, PULAPURA S K, GROSS R A.Liquid cyrstalline characteristics of site-selectively-modified chitosan[J].Macromolecules,1993,26(22):5999-6006
[4]TERBOJEVICH M, COSANI A, FOCHER B et al.Chitosans from euphusia supebraI: solution properties[J].,1992,18(l):35-42
[5] RATTO J A, HATAKEYAMA T, BLUMSTEIN R B. Differential scanning calorimetry investigation of phase transitions in water/chitosan systems[J][J].,1995,15(36):2915-2919
[6]FREIBERG S and ZHU X X.Polymer microspheres for controlled drug release[J].International Journal of Pharmaceutics,2004,282:1-18
[7]黎观红，翟明任，晏向华等.VC的营养和应用研究进展[J].,2001,4:28-32
[8]闻芝梅，陈君石.现代营养学[M][J].,1988,:140-153
[9]ZHAO J, WANG Z N, WEI X L, et al.Phase behavior and rheological properties of the lamellar liquid crystals formed in dodecyl polyoxyethylene polyoxypropylene ether/water system[J].,2011,50A:641-649
[10]何曼君,陈维孝,董西侠.高分子物理[M][J].,1990,:-
[11]LU R, GAO X.Study of rheological properties of soy bean lipoid[J].,2006,27(4):51-54
[12]SIDDING M A, RADIMAN S, MUNIANDY S V, et al.Structure of cubic phases in ternary systems glucopone/water/hydrocarbon[J].Colloid Sur A Physicochem Eng Aspects,2004,236:57-67
[13]PORTER R S, JOHNSON J F.The entanglement concept in polymer systems[J].Chem.Rev,1966,66(1):1-27
[14]段炼，薛宇，李国英.天然胶原的稳态流变性能和数学模拟[J].,2010,12(41):2068-2071
[15]魏娟，王仲妮，赵静，吴同浩.非离子表面活性剂溶致液晶的流变性质[J].,2010,12(5):210-212
[16]冯尚华，王红霞.温度对两种不同立方相液晶流变性的影响[J].,2006,23(9):863-866
[17]王仲妮，赵静，周武等.层状液晶的流变性质和释药行为研究[J].,2011,13(5):157-161