Preparation of Compound Magnetic Nanoparticle Fe3O4@Si-C8/C18 and Its Application in Purification of Veterinary Drugs

Abstract

Abstract: In this paper, we first applied compound magnetic nanoparticle Fe3O4@Si-C8/C18 to purify veterinary drugs, and co-precipitation method was employed to synthesize the precursor of magnetic nanoparticles. The surface of nanoparticle precursor was silicified in ethanol and modified with C8 (octyltrimethoxysilane)/C18 (octadecyltrimethoxysilane) to prepare composite magnetic nanoparticle Fe3O4@Si-C8/C18. The compound magnetic nanoparticles were characterized by TEM, X-ray, magnetic performance analysis, and infrared spectroscopy. These compound magnetic nanoparrticles revealed high uniformity with adjustable particle diameters of 100－1000 nm. Therefore, after several layer-by-layer modifications, the compound magnetic nanoparticle revealed the same magnetic intensity as its original precursor. In order to validate their application possibility in the purification of veterinary drugs, purification of chloramphenicol residues in bean sprout was conducted using these magnetic nanoparticles. The results demonstrated that these compound magnetic nanoparticles had extensive application value for the purification and enrichment of micromolecules, especially in the field of food safety.

Key words: compound magnetic nanoparticle, C8/C18, purification of veterinary drug

CLC Number:

S859.84

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