FOOD SCIENCE ›› 2012, Vol. 33 ›› Issue (20): 109-112.

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Optimization of Extraction Process for Total Flavonoids from Stems and Leaves of Scutellaria baicalensis Georgi

  

  • Received:2011-07-31 Revised:2012-09-18 Online:2012-10-25 Published:2012-11-09

Abstract: The extraction of total flavonoids from stems and leaves of Scutellaria baicalensis Georgi by ethanol extraction was optimized using an L9(34) orthogonal array design. One-factor-at-a-time method was used to investigate the effects of temperature, extraction time, ethanol concentration and solid/solvent ratio on extraction efficiency. The optimum conditions for the extraction of total flavonoids were determined as three extraction cycles with 70% ethanol at a solid/solvent ratio of 1:18 (g/mL), 70 ℃ for 2.0 h each. Under these conditions, the yield and purity of crude total flavonoid extract were 21.02% and 1.39%, respectively.

Key words: Scutellaria baicalensis Georgi, total flavonoids, extraction process