Separation, Purification and Structural Identification of Antiarrhythmic Constituents in Cephalosporium sinensis Mycelia

FOOD SCIENCE ›› 2012, Vol. 33 ›› Issue (21): 149-152.

Separation, Purification and Structural Identification of Antiarrhythmic Constituents in Cephalosporium sinensis Mycelia

Received:2011-09-06 Revised:2012-09-28 Online:2012-11-15 Published:2012-11-09
Contact: Zheng-Rong ZOU E-mail:zouzhr@163.com

Abstract

Abstract: Objective: To study antiarrhythmic constituents in Cephalosporium sinensis mycelia. Methods: Antiarrhythmic constituents in Cephalosporium sinensis mycelia were separated and purified by silical gel column chromatography and ODS RP C18 HPLC and structurally identified according to physio-chemical properties and spectral data. Results: Five active compounds were separated from the water saturated butanol-soluble fraction of ethanolic extract from Cephalosporium sinensis mycelia, including uridine, thymidine, 2’-deoxyuridine and uracil. Conclusion: The main antiarrhythmic constituents in Cephalosporium sinensis mycelia are nucleosides.

Key words: Cephalosporium sinensis, antiarrhythmic, active constituents

CLC Number:

R932

[1]	QIAO Jinli, QIN Dong, GUO Liangchuan, FEI Xiaohui, ZHANG Yan, HUO Junwei. Recent Progress in Bioactive Constituents of Lonicera caerulea L. Fruit and Their Health Benefits [J]. FOOD SCIENCE, 2020, 41(9): 276-284.
[2]	YU Jing, WEN Rongxin, YAN Qingxin, CHEN Qian, QIN Ligang. Bioactive Constituents of Allium and Their Physiological Functions: A Review [J]. FOOD SCIENCE, 2020, 41(7): 255-265.
[3]	LAN Mengliu, YANG Lili, YAN Guijie, ZHU Huaichang, LI Xiaoyan, XU Wen, WU Shuisheng. Comparative Analysis of Functional Composition of Different Parts of Alisma orientale (Sam.) Juzep. for Medicinal and Food Purposes [J]. FOOD SCIENCE, 2020, 41(20): 167-174.
[4]	CHEN Hui, MA Xuan, CAO Lixing, ZHAO Chong, YIN Shutao, ZHANG Qiu, HU Hongbo. Recent Progress in the Mechanism behind Exercise-Induced Fatigue and Dietary Bioactive Components against Fatigue [J]. FOOD SCIENCE, 2020, 41(11): 247-258.
[5]	KANG Wenli, CHEN Liang, HE Bo, WU Can, ZHOU Shangting. Changes of Aroma-Active Components in High-Salt Liquid-State Fermented Soy Sauce before and after Sterilization [J]. FOOD SCIENCE, 2019, 40(18): 253-258.
[6]	ZHANG Lu, LIU Pengfei, TU Zongcai, XIE Xing, ZHANG Shuya, SHA Xiaomei, WANG Hui, DAI Huajian. Comparison of Antioxidant Activity and Enzyme Inhibitory Activity of Different Plant Parts of Torreya grandis cv. Merrillii [J]. FOOD SCIENCE, 2018, 39(10): 78-83.
[7]	TU Zong-cai1,2，ZHANG Qiu1，WANG Hui1，ZHANG Lu1，SHA Xiao-mei1，CHEN Li-li1，ZHANG Qiu-ting1，ZHANG Lan1. Effect of Drying Methods on Chemical Composition and Bioactivity of Aqueous Extract from Roselle [J]. FOOD SCIENCE, 2013, 34(21): 47-50.
[8]	SUN Jie, WANG Yan-Jie, ZHU Lu-Ying, YANG Run-Ya. Study on Antifungal and Antioxidant Activities of Alcohol Extract of Gelidium amansii [J]. FOOD SCIENCE, 2007, 28(10): 53-56.
[9]	ZOU Zheng-rong1,2,WANG Nai-li2,YAO Xin-sheng. Antiarrhythmic Effects on Neonatal Rat Cardiac Myocytes of Extracts from the Mycelia of Cephalosporium sinensis [J]. FOOD SCIENCE, 2006, 27(12): 745-747.
[10]	LIU Jing-Sheng, YUAN Yuan, TIAN Zhong-Hua. [J]. FOOD SCIENCE, 2003, 24(6): 165-168.

Separation, Purification and Structural Identification of Antiarrhythmic Constituents in Cephalosporium sinensis Mycelia

RichHTML

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 10

Recommended Articles

Metrics

Comments