FOOD SCIENCE ›› 2012, Vol. 33 ›› Issue (21): 303-307.

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A Comparative Study of the Improving Effects of Enzymatic Bone Fine Powder and Enzymatic Bone Ordinary Powder on Bone Density in Rats

Wen-Li ZHU1,   

  • Received:2011-09-23 Revised:2012-09-01 Online:2012-11-15 Published:2012-11-09
  • Contact: Wen-Li ZHU E-mail:zhuwenli@bjmu.edu.cn

Abstract: Objective: To compare the improving effects of enzymatic bone fine powder (EBFP) and enzymatic bone ordinary powder (EBOP) on bone density and apparent calcium absorption rate (ACAR) in rats. Methods: Totally 100 female SD rats at 4 weeks old were randomly divided into 10 groups of 10 rats each including high-, medium- and low-dosage EBFP and EBOP groups, high-, medium- and low-dosage calcium carbonate (CC) groups (550.0, 283.3 mg and 216.7 mg of calcium in per 100 g of feed, respectively), and low calcium (LC) control group (150 mg of calcium in per 100 g of feed). After 13 weeks of feeding, ACAR, bone calcium content, bone density, bone length and bone constant weight in rats were determined. Results: Femur bone density in EBFP groups was significantly higher than that in LC group (P>0.05), but was not lower than that in the CC control groups. Femur bone density in EBOP groups was significantly higher than that in LC group, but femur bone calcium content and distal femoral bone mineral density were lower in low-dosage EBOP group than CC group (P<0.05). There was no significant difference (P>0.05) in ACAR, bone calcium content, bone density, bone length, total food utilization and body weight between EBFP and EBOP groups at the same dosage. Femur bone constant weight was higher in medium-dosage EBFP group than medium-dosage EBOP group (P<0.05). Conclusion: Enzymatic bone fine powder can increase bone density in rats, while it is uncertain whether enzymatic bone ordinary powder can do so. 

Key words: enzymatic bone fine powder, enzymatic bone ordinary powder, bone mineral density (BMD), apparent calcium absorption rate

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