Optimization of Ultrasonic-Microwave Assisted Extraction of Chlorogenic Acid from Flos Lonicerae

Abstract

Abstract: The current study was carried out to optimize the ultrasonic-microwave assisted extraction of chlorogenic acid from Flos Lonicerae. The extraction yield of chlorogenic acid was investigated with respect to temperature, ethanol concentration, solid-to-solvent ratio, microwave power and irradiation time. The combined use of ultrasonic and microwave provided higher extraction efficiency than their individuals. An extraction yield of chlorogenic acid of 5.93% was obtained when ultrasonication for 30 min followed by microwave irradiation at a power of 400 W for 5 min was used for the extraction of Flos Lonicerae with 70% ethanol at a solid-to-solvent ratio of 1:15 (g/mL).

Key words: Flos Lonicerae, ultrasonic, microwave, chlorogenic acid, extraction yield

CLC Number:

中图分类号：R284. 2 文献标识码: A

References

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