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Ultrasonic Extraction of Lycorine and Galanthamine from Red Spider Lily Bulb (Lycoris radiate)

WANG Peng,TIAN Chun-lian,LIU Xiao-pan   

  1. Hunan Province Key Laboratory of Forest Products and Chemical Industry Engineering, Jishou University, Zhangjiajie 427000, China
  • Online:2013-10-25 Published:2013-09-28

Abstract:

Optimal conditions for the ultrasonic extraction of lycorine and galanthamine from red spider lily bulb were
established in this study. The compounds were determined simultaneously by HPLC. The effects of extraction time,
temperature, ultrasonic treatment time and material-to-solvent ratio on extraction efficiency were investigated. Analysis
of variance showed that three extraction parameters in the decreasing order of importance were extraction time, ultrasonic
radiation time and temperature. An extraction temperature of 70 ℃ and 2.5 h extraction followed by 30 min ultrasonic
treatment repeated in sequence twice proved optimal, which provided maximum yields of lycorine and galanthamine, 0.1561%
and 0.0253%, respectively.

Key words: red spider lily, lycorine, galanthamine, ultrasonic treatment