Abstract:

The aim of this research was to access the release of total phenolics, flavonoids and procyandines from
Choerospondias axillaris fruit peel during in vitro simulated gastro-intestinal digestion and solvent extraction, and the
bioavailability of the components were also studied by simulating intestinal adsorption using dialysis. Results indicated
that the phenolic compounds were mainly released in the gastric phase. After digested in simulated gastric juice for 1 h,
the release amount of polyphenols, flavonoids and procyanidins were 73.72, 38.55 and 37.53 mg/g, respectively; after
2 h intestinal digestion, the release amount of polyphenols and flavonoids increased by 10.29 and 8.78 mg/g, respectively,
however, 17.87% of procyandines were degraded. In addition, the contents of polyphenols, flavonoids and procyanidins
in the dialysis bag were 5.94, 5.48 and 3.21 mg/g, and the corresponding bioavailability was 7.07%, 11.59% and 10.42%,
respectively. Therefore, flavonoids are the most available component for human adsorption and utilization. Different
treatment methods released phenolic compound in the order: simulated gastro-intestinal digestion < traditional hot water
extraction < ultrasonic assisted ethanol extraction.

Key words: Choerospondias axillaris fruit peel, simulated gastro-intestinal digestion, solvent extraction, total phenolics, total flavonoids, procyandines