Abstract: Proteomic analyses have been performed to study the adaptation and response of microorganisms to various stresses. Non-thermal sterilization technologies have gained significant attention since they have the potential to provide new food products with better nutritional properties than traditional ones. Non-thermal sterilization can cause changes in proteins in microorganisms, which are related to microbial inactivation. This review addresses the application of proteomics in non-thermal sterilization technologies, which is important for understanding the mechanism of non-thermal sterilization from the perspective of molecular biology.

Key words: proteomics, non-thermal sterilization, differentially expressed proteins, sterilization mechanism