FOOD SCIENCE ›› 2025, Vol. 46 ›› Issue (18): 425-396.doi: 10.7506/spkx1002-6630-20250128-202

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Progress in Understanding the Role and Mechanism of Action of Tea in Alleviating Colitis

SUN Yuning, LIU Qianfen, LIU Dan, LI Daxiang, CAI Huimei, CHEN Guijie   

  1. (1. National Key Laboratory for Tea Plant Germplasm Innovation and Resource Utilization, Key Laboratory of Tea Biology and Tea Processing of Ministry of Agriculture and Rural Affairs, International Joint Research Laboratory of Tea Chemistry and Health Effects of Ministry of Education, Hefei 230036, China; 2. School of Tea Science, Anhui Agricultural University, Hefei 230036, China;3. Anhui Provincial Joint Construction Key Laboratory of Industrial New-Style Tea Beverage Green Manufacturing, Anhui Provincial Key Laboratory of Food Safety Monitoring and Quality Control, School of Food and Nutrition, Anhui Agricultural University, Hefei 230036, China; 4. Institute of Health and Medicine, Hefei Comprehensive National Science Center, Hefei 230036, China)
  • Online:2025-09-25 Published:2025-08-19

Abstract: Inflammatory bowel disease (IBD) is a common chronic intestinal inflammatory disorder, primarily including ulcerative colitis (UC) and Crohn’s disease (CD), with a complex pathogenesis involving multiple interacting factors. In recent years, intervention with tea and its active components in IBD and their action mechanisms have garnered considerable research attention. Research indicates that tea and its functional components can alleviate colitis through multiple pathways, including regulating inflammatory factors and related signaling pathways, modulating immune function, repairing the intestinal barrier, and regulating the gut microbiota and metabolites. This review summarizes recent progress on the role of tea in mitigating colitis, with a focus on its action mechanism, aiming to provide new insights and scientific evidence for the prevention and treatment of IBD.

Key words: tea; bioactive components; inflammatory bowel disease; gut microbiota; mechanism of action

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