in vitro and in vivo Antioxidant Activities of Varous Areca Nut Extracts

doi:10.7506/spkx1002-6630-200907051

FOOD SCIENCE ›› 2009, Vol. 30 ›› Issue (7): 225-228.doi: 10.7506/spkx1002-6630-200907051

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in vitro and in vivo Antioxidant Activities of Varous Areca Nut Extracts

YUAN Lie-jiang1,2 LI Zhong-hai1 ZHENG Jin-xing1

(1.College of Food Science and Engineering, Central South University of Forestry and Technology, Changsha 410004, China
2.China Agricultural Product and By-product Quality Inspection Center (Hunan), Changsha 410007, China)

Received:2008-06-07 Revised:2008-08-30 Online:2009-04-01 Published:2010-12-29
Contact: YUAN Lie-jiang1,2 E-mail:yuanliejiang@163.com

Abstract

Abstract:

The in vitro and in vivo antioxidant activities of Hainnan areca nut extract with 70% methanol aqueous solution (crude extract) and petroleum ether soluble fraction (fraction I ), chloroform soluble fraction (fraction II), ethyl acetate soluble fraction (fraction III) and water soluble fraction (fraction IV) of this extract and were investigated by measuring hydroxyl radical scavenging capacity and white mouse experiment. The results showed that the crude extract, fraction III and fraction IV present higher hydroxyl radical scavenging activity and the scavenging rates are all above 53%. In in vivo study, these three extracts are able to increase serum SOD levels at the doses of 1.0 mg/ml (low dose), 3.0 mg/ml (medium dose) and 5.0 mg/ml (high dose) by 0.1 ml/10 g bw (p<0.05), and except for the high dose of fraction III, decreases in the serum MDA content are found in mice administrated with these three extracts. In conclusion, these three extracts of areca nut have strong antioxidant activity both in vitro and in vivo.

Key words: areca nut extract, hydroxyl radical, antioxidant activity, SOD, MDA

CLC Number:

Q507

YUAN Lie-jiang1,2 LI Zhong-hai1 ZHENG Jin-xing1. in vitro and in vivo Antioxidant Activities of Varous Areca Nut Extracts[J]. FOOD SCIENCE, 2009, 30(7): 225-228 https://doi.org/10.7506/spkx1002-6630-200907051

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in vitro and in vivo Antioxidant Activities of Varous Areca Nut Extracts

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