FOOD SCIENCE ›› 2009, Vol. 30 ›› Issue (6): 39-42.doi: 10.7506/spkx1002-6630-200906003

Previous Articles     Next Articles

Synthesis of Carboxymethyl Chitosan by Phase Transfer Catalytic Method and Its Characterization

XIAO Yu-liang，LI Yu-qin，XIA Cheng-cai，YOU Gui-rong，HAN Jun-fen，DUAN Gui-yun，ZHANG Hai-xia   

  1. (College of Pharmaceutical Sciences, Taishan Medical University, Taian 271000, China)
  • Received:2008-03-13 Revised:2008-08-01 Online:2009-03-15 Published:2010-12-29
  • Contact: XIAO Yu-liang E-mail:111925wj@163.com

RichHTML

0

PDF (PC)

286

Abstract:

In this study, preparation of carboxymethyl-chitosan (CMC) with phase transfer catalyst was described. Firstly, the effects of carboxymethylation conditions on the degree of substitution (DS) and solubility of CMC were investigated, and the optimum catalyst, reaction temperature, reaction time, volume ratio of water to alcohol are 6% of triethylbenzylammonium (TEBA), 55 ℃, 4 h and 1:4, respectively. Under these conditions, the DS and the solubility of CMC reach 1.147 and 98.87%, respectively. Then the chemical construction of CMC was characterized by Fourier-transformed infrared (FTIR) and X-ray photoelectron spectroscopy (XPS). The results showed that the carboxymethylation mainly occurs on hydroxy group in C6 site of chitosan.

Key words: carboxymethyl chitosan (CMC), phase transfer catalysis, characterization

CLC Number: