FOOD SCIENCE ›› 2007, Vol. 28 ›› Issue (9): 250-252.

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Supercritical CO2 Anti-solvent Crystallizing Puerarin:Modeling

 ZHANG  Wen-Cheng   

  1. Engineering Research Center of Bio-process,Ministry of Education,Hefei University of Technology,Hefei 230009,China
  • Online:2007-09-15 Published:2011-11-22

Abstract: With extract of pueraria as experimental material,by the supercritical CO2 anti-solvent technology the puerarin was purified.The effects of crystallization pressure,temperature and time were studied,and the purity of puerarin was detected with high performance liquid chromatography.The model of purification of pueratin about crystallization pressure,temperature and time was established with response surface methodology(RSM).Results showed that the relative deviation of actual value to predicted value was 3.37%.

Key words: supercritical CO2 anti-solvent, puerarin, purification, response surface methodology