Abstract: Quinolones bactericides are artificial nalidixic acids derivates which can kill bacterias by inhibiting their DNA-gyrase. They were widely applied because of their good absorbability, long half life and so on. But they have side effects on human, So now people paid much attention to quinolones residues in meat and eggs since quinolones had been often used in livestock and fishfarm industries. Therefore, the European Union(EU) has set tolerance levels for these compounds as maximum residue limits (MRLs) in 1990s. At present the common determination methods are also HPLC and other correlative methods, for example, HPLC-UV, HPLC-FD, LC-MS-MS. In addition, there are also Fluorescence spectrometry, CE and ELISA which are common determination methods for quinolones residues as well.

Key words: quinolones, residue, analysis