Abstract: This paper summarize growth environment and the chemical ingredients of Rhodiola ;at the same time, from theview of Physiology and Biological Chemistry, it illuminates mechanism of Rhodiola of delay of peripheroneural fatigue bymeans of rising in hapatic glycogen store、increasing in blood circulation、decreasing in accumulation of blood lactic acid andeffect never center- fatigue by keeping ordinary content of SEROTONIN(5-HT); the influence of Rhodiola on the theory ofmultiple elements fatigue embodied on experiment about body weight load swimming to exhaust in mice and analyze of contentof hapatic glycogen after swimming.

Key words: Rhodila, anti-fatigue mechanism, pharmacological study