Micro-extraction Determinationof Alkylphenolic Acids in Chinese Patent Medicine GBE with n-hexane Extract by LiquidChromatography - mass Spectrometry

Abstract

Abstract: With n-hexane extraction, the qualitative and quantitative analyses of alkylphenolic acids in Chinese patent medicineGBE (Ginkgo Bilobu Extract) were carried out with liquid chromatography-UV detector and mass spectrometry detector. Then-hexane was proven to be a very efficient extracting reagent, and few interfering materials were coextracted. Under the optimizedexperimental conditions, the recovery was 98.9%(n=5), the detection limit was 0.1μg/g, and the linear range was between 0.5～10μg/g for Ginkgo Biloba alkylphenolic acid of molecular weight of 346.

Key words: GBE, alkylphenolic acids, HPLC-MS

DENG Yong-Zhi, YUAN Dong-Xing, CHEN Meng, JIN Xiao-Ying, WANG Yong-Mei. Micro-extraction Determinationof Alkylphenolic Acids in Chinese Patent Medicine GBE with n-hexane Extract by LiquidChromatography - mass Spectrometry[J]. FOOD SCIENCE, 2003, 24(12): 107-110.

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Micro-extraction Determinationof Alkylphenolic Acids in Chinese Patent Medicine GBE with n-hexane Extract by LiquidChromatography - mass Spectrometry

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