Abstract: The minimum inhibition concentrations (MICs) of single clove essential oil,single cinnamon essential oil and their comination were determined by the same ratio dilution method respectively,and their combined antiseptic effects were evalu-ated by fractional inhibitory concentration (FIC). The results showed that the combined use of colve and cinnamon essential oils has synergetic inhibition effect on Bacillus subtilis,Aspergillus niger and Saccharomyces rouxii,and plus effect on Escherichia coli,Penicillium sp and Saccharomyces cerevisiae,but no antagonistic effects on all the tested microorganisms in this experiment. The combined use of colve and cinnamon essential oils shows different inhibition effects on different bacteria. Compared with single use of colve or cinnamon essential oil,their combined use shows 8-time inhibition effect on Bacillus subtilis,and 4-time inhibition effects on Staphylococcus cremoris,Aspergillus niger and Saccharomyces rouxii.

Key words: clove essential oil, cinnamon essential oil, combined antisepsis