Abstract: Under the conditions of cellulase amount 1.5% (V/V),pH 4.5,50 ℃ and time 5 h,the extract of mixture of three Chinese traditional medicines (kudzu poot,Hovenia dulcisT hunb and villous amomum fruit,dry weight ratio 1:2:2) was obtained,in which the total flavonoids content is 6.48μg/ml. The extract was added to fermentation medium of Ganoderna lucidum.T he fermentation conditions in 10-L fermenter were optimized by L9(34) orthogonal test. The results showed that the optimum ermentation conditions are as follows: volume of the medium added with extract of Chinese traditional medicines 80%,culture temperature 30 ℃,mixing speed 200 r/min and fermentation duration 144 h. And the optimum formula of tea beverage is fermentation broth 50%,tea extract liquid 25%,β-CD 1% (W/V) and sugar syrup (45BX’) 6%. It was proved that the mixed tea beverage has anti-alcoholic function by the animal test.

Key words: Ganoderna lucidu, mfermentation of medium added with extract of Chinese tradtional traditional medicine, tea beverage, anti-alcoholic