Abstract: On the basis of separation and purification of chlorogenic acid(CA) in dandelion,the β-cyclodextrin(β-CD) inclusion of CA and identification were studied in this paper. The comparison of the differences of the anti-lipid peroxide effects between CA and its inclusion(β-CD -CA) was carried out. The conditions of the chemical simulation, the clearing function on the form of superoxide anion(O·2) and hydroxyl radical(·OH), the inhibition on UV-induced hemolysis of red blood cell(RBC) and the increase of peroxide value(POV) and acid value(AV) of oil in the storge at high temperature of CA andβ-CA were evaluated in this paper too. The results showed that both CA and β-CA have clearing function on O·2 and· OH, and effective inhibition on UV-induced hemolysis of RBC. They can notablely stave the increase of POV value and AV value of oil. The antioxidative function ofβ-CD -CA was better than CA, and exceeded tea polyphenols (TP) which was commonly used as positive control drug in some aspect. The reason that the β-CD -CA has better antioxidative function may be due to the enhancement of stability after inclusion.

Key words: dandelion； chlorogenic acid； inclusion； &beta, -cyclodextrin； antioxidation - -；