Abstract: Object:The purpose is to compare the effects of soybean isoflavones and free aglycone for improving mouse humoral immunity.Methods:The mice were instilled with soybean isoflavone and aglycone respectively 40～100mg/kg for 21day continually.Immunological analysis showed the phagacytosis index and the weight of spleen.The results indicated that both the soybean isoflavones and the free aglycone can significantly improve the phagocytosing function of celiac macrophage,and stimulate the growth of spleen and thymus.The trigger effects in the female mice are much better than the male mice for the administration of either soybean isoflavones or free aglycone,whereas the absorbing effects of free aglycone are better than those of soybean isoflavones.

Key words: soybean isoflavone, aglycone, immunity function