Abstract:  Bacillus stearothermophilus As 1. 999 and S. cerevisiae As 2. 1364 were sterilized high hydrostatic pressure (HHP) with different pH value and different kinds of organic acid. The result,showed that the effects of sterilization by above mentioned enviromental conditions cooperating with HHP yield no notable influnce, the main effect on sterilization is the pressure.

Key words: S. cerevisiae B. stearothermopphilus High hydrostatic pressure pH Organic acid Sterilization combination