Abstract:  The pattern of ultra high pressure (UHP) sterilization was studied and summarizad in this paper. The pressure tolerance of most non-spore-forming microorganisms were low. They could be inactived by pressure up to 450MPa at room temperature, and their rates of inactivation followed first order kinetics. Low temperature (sub zero)or above room temperature were benefit to UHP sterilization. lt needed higher pressure to inactive spore formers, and usually also needed heating or other treatments to combine with UHP. The survival curves of spores did not obey first ordet rate equation. Temperature, medium and other factors affected the pattern and effect of UHP sterilization. Oscillatory and pulsed UHP were effective methods for the sterilisalion of baroduric spores.

Key words:  , Ultra high pressure (UHP) Sterilizalion Kinetics；