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Advances in the Application of Aptamers to Detect Mycotoxin in Foods

DU Bingyao1,2,3,4, WEN Fang1,3,4,*, WANG Jiaqi1,3,4, ZHENG Nan1,3,4, ZHANG Yangdong1,3,4, ZHAO Shengguo1,3,4   

  1. 1. Laboratory of Quality & Safety Risk Assessment for Dairy Products (Beijing), Ministry of Agriculture, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China; 2. College of Animal Science, Xinjiang Agricultural University, Ürümqi 830052, China; 3. Milk and Dairy Product Inspection Center (Beijing), Ministry of Agriculture, Beijing 100193, China; 4. State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China
  • Online:2016-09-15 Published:2016-09-22

Abstract:

In recent years, food quality and safety events have occurred frequently in China and they have posed serious
health hazards. Consequently, there are rising concerns about the issue of food safety and quality. Aptamers are singlestranded
DNA or RNA molecules obtained by systematic evolution of ligands by exponential enrichment (SELEX). They
possess high affinity to target molecules. Aptamers have the advantages of low cost, simple operation, high sensitivity and
selectivity. Therefore, they have been applied for the determination of proteins and mycotoxins. This paper reviews the latest
advances in the application of aptamer-based methods for the detection of mycotoxins in foods.

Key words: nucleic acid aptamer, detection, food, mycotoxin

CLC Number: