Abstract: Mycotoxins are widely distributed, heavily polluting, and difficult to prevent and control. During the whole process from farm to table, agricultural products are easily polluted by mycotoxins, posing serious threats to human and animal health as well as ecological and environmental safety. According to statistics, more than 75% of mycotoxin contamination in agricultural products is caused by a mixture of multiple mycotoxins. Therefore, establishing a highly sensitive and high-throughput mycotoxin detection technology is a major challenge in the field of food safety testing. This article summarizes the progress in the multiple detection of mycotoxins in the past five years, including high performance liquid chromatography-tandem mass spectrometry, immunochromatography, chemical colorimetry, electrochemistry, chemiluminescence and fluorescence spectroscopy. The applications of these methods in the multiple detection of mycotoxins and the problems to be solved are analyzed, and prospects are discussed.

Key words: agricultural products; mycotoxins; aptamers; multiple detection