Recent Progress in Understanding the Characteristics and Mechanisms of Flavan-3-ols Absorption and Metabolism in Humans

doi:10.7506/spkx1002-6630-20200605-069

FOOD SCIENCE ›› 2021, Vol. 42 ›› Issue (21): 213-222.doi: 10.7506/spkx1002-6630-20200605-069

• Reviews • Previous Articles Next Articles

Recent Progress in Understanding the Characteristics and Mechanisms of Flavan-3-ols Absorption and Metabolism in Humans

LIU Ruonan, CHEN Wanbing, YAN Fangfang, LIU Min, LU Qun, YANG Hong, LIU Rui

(1. Key Laboratory of Environment Correlative Dietology, Ministry of Education, College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430000, China; 2. Wuhan Engineering Research Center of Bee Products on Quality and Safety Control, Wuhan 430000, China; 3. Key Laboratory of Urban Agriculture in Central China, Ministry of Agriculture and Rural Affairs, Wuhan 430000, China)

Online:2021-11-15 Published:2021-11-23

Abstract

Abstract: Flavan-3-ols are one of the most abundant classes of dietary polyphenols in the human diet. In recent years, flavan-3-ols have attracted much attention because many studies have found that they are associated with reduced risks of many chronic diseases and alleviation of metabolic syndromes. However, the role of flavan-3-ols in the body depends to a certain extent on their absorption and metabolism after being ingested, especially their catabolism by intestinal microbes. In this context, this article focuses on reviewing the signaling pathways related to the absorption, metabolism and biotransformation of flavan-3-ols, which will be helpful for understanding their biological effects in the body.

Key words: flavan-3-ols; absorption; intestinal microbes; metabolic mechanism

CLC Number:

TS201.2

LIU Ruonan, CHEN Wanbing, YAN Fangfang, LIU Min, LU Qun, YANG Hong, LIU Rui. Recent Progress in Understanding the Characteristics and Mechanisms of Flavan-3-ols Absorption and Metabolism in Humans[J]. FOOD SCIENCE, 2021, 42(21): 213-222.

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Recent Progress in Understanding the Characteristics and Mechanisms of Flavan-3-ols Absorption and Metabolism in Humans

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